Few things we have to take care:

1. Learn positives of others, as every one has bath positives and negatives

2. Follow the ego state: I am OK, you are also OK!

3. Don't follow the ego states: I am OK, you are not OK! and I am not OK, You are OK!

4. Take every situation as learning object.

5. Etc. ... .

Dear Sribas,

Our ancestral ignorance lies in two things only: where we come from, and why we die. To alleviate this profound ignorance that torments us, arose, over time, religion, philosophy and science. Therefore, estimated Sribas, we still have everything to learn.

Dante.

Ignorance is expensive, and knowledge is cheaper. In order to reduce cost in life, increase more knowledge and decrease as much ignorance as possible. The more we share knowledge, the more we receive in return and the more we all could benefit. The more we are ignorance, the less we understand anyone or anything.

We need to learn that the dynamics of our mind is governed by the dichotomous feedback mechanism behind the knowledge-ignorance interplay.

Paul, I am not very convinced by "more we share knowledge, the more we receive in return and the more we all could benefit"; is this always correct? What about "more we are ignorance, the less we understand anyone or anything" failing to stop an optimist from receiving more in return and benefiting from it.

There is not a unique answer, I agree with Sribas. So, maybe we have to improve our self-knowledge in order to decide what we have to learn:exactly the sectors where we have more ignorance.

TED gives the opportunity for knowledge enrichment

http://www.everwideningcircles.com/tag/tedtalk/?gclid=CjwKEAiAjsunBRCy3LSlz_PJqCgSJACJY7yKmQq20Nr8ixRhOoAYtHf8ngz1_nEQvy1-LWSe1j5cGBoCsH3w_wcB

The development of sciences, have produced a huge amount of "knowledge", which seem to be impossible to acquire! Parallel to this formal knowledge, there is something called non-analytic, holistic knowledge, which is based on our "intuition". Thus the only way to have a workable knowledge is to develop a high fidelity intuition. This will give you a sense of non-ignorance although you may know a small part of scientific knowledge! 

Dear @Sribas, I do agree with my friend @Costas on Holistic approach to Intellectual Development! "...Without the breath offered by a general education program, students tend to develop illusionary conceptions of themselves and others which are obstructive of clear thinking and mutually beneficial human exchange. The struggle for knowledge and clear thinking is not simply against ignorance, but more importantly against illusion. Clear independent thinking seeks truth below the surface and behind the images..."

http://web.stcloudstate.edu/lstripp/holistic.htm

Ignorance results from logistic/mental constraints. Given the huge amount of new information produced every day, much of it will obviously be ignored. But then how to select what should not be ignored?

Dear Kundu's answer is great.

Try this too

http://www.taoism.net/theway/ignorance.htm

We surely need to learn several lessons of life and other lessons to reduce our ignorance, and I agree with Roland.  I also like this: 'We are ignorant on humane level because real humanitarian values have never been instilled in us. Our system of education if anything, prepares us only for professional life completely missing the fact that while being professionals, we also should be able to relate to one another in a respectful way.'

https://ca.answers.yahoo.com/question/index?qid=20131225025313AAtiCCq

But ignorance might be caused by biology-based constraints? What can an ant do when its brain has been organized not to perceive certain 'realities' in life? Perhaps humans are symbolic ants compared to other beings in the universe? 

Dear Sribas: The answer may be summarized in one word: humility, given that arrogance is normally associated to stupidity and ignorance.

Dear Marcel,

Yes, there are a lot of information that it is harm if we perceive it! For example in order to perceive the macro-world as we know it, we should hide information in other levels of reality. This does not mean that we are "ignorant", but rather mean that we choose to perceive what we need to!

Dear Sribas,

Dear All,

Many RG threads during years stressed that the most important instrument to surviving and living peacefully/humanly must be educational opportunity and realized education for everybody. Learning is an infinite process. It needs two conditions: opportunities in the wide sense of word and the intention to learn. Providing learning opportunity needs financial and behavioural (cultural) conditions. Innate desire to learn needs behavioural (cultural) backgroungs.

We need to learn the lesson of perspectivism, that is, the ability to look at reality from the varying perspectives of those around us.  Then we must learn to integrate all these perspectives to arrive at truths on our own.

Forget ego!

Take every stimuli and interaction as learning object.

Take positives, think and avoid negatives! 

Every human being needs in shock therapy from time to time, as we say "fight fire with fire". And what?There are no wonders- you can't change the situation around, where all is measured by money only and you have burned a lot of times because of it..The care about children, old persons is a main thing.Only begin to cure the ill...and you'll understand your own nothingness. In the family there are a lot of weak links...It's easy to be wise after the event.Intuition? Unfortunately, you can't predict misfortunes in instability and chaos.Every minute you can be fired from work and loose the last piece of bread.People are becoming old not from the time or age, but from disappointments.Fighting for place under the sun it soon evening will shut in and your Sisypheon labor will turn to nonsense. Perspectives?

I believe that I must learn that my knowledge is imperfect and the way I practice my knowledge isn't perfect.  I must learn HUMILITY rather than trying to think I know much.  Then I will increase some learning and reduce some ignorance.  And there is more of ignorance to reduce each day...

Dear @George, enormous number of questions without single answer may mean that questions were been ignored as too tough, or too simple. I would not say that we are ignorant in virtual way, but serious people who ignore it for obvious reasons.

Getting good experience and learning from it.

Real knowledge is to know the extent of one's ignorance.

--- Confucius

Becoming happier requires first, a commitment to making happiness a priority; and second, a willingness to learn, practice and ultimately master the key “disciplines” associated with happiness.

http://www.thehappinessinstitute.com/freeproducts/docs/The%207%20Most%20Commonly%20Asked%20Questions%20About%20Happiness%20and%20Answers%20from%20Dr.%20Happy..pdf

It's fine to celebrate success but it is more important to heed the lessons of failure.

--- Bill Gates

Dear All,

One of the most crucial rule of life has been during ages the permanent learning. This is the elementary approach to adapt to new conditions. We are living now in the age of informatics. Many may think that this has strengthened the importance and possibility of learning. If you have a look at the general educational standards of society, you can recognise that people’s knowledge has been structurally changed : they have had much often superficial or little detail information, but holistically they know less than earlier.  Another attribute is the appearance of the high amount of fake information. In summary, one of the most important controlling means became the modification of information availability – often retaining information - as well as the politically co-ordinated learning process.