Hello Wendy Baker Smemoe. Can you tell us what the variables are for the multiple pre/post comparisons? I'm trying to work out whether you have multiple (different) dependent variables vs one dependent variable measured under multiple (different) conditions.

If you do have multiple DVs, the next question might be whether they are commensurable.

Finally, bear in mind that a paired t-test is equivalent to a one-sample t-test on the paired differences. (This might help simplify your analysis a bit.)

Thanks for clarifying. HTH.

Wendy Baker Smemoe, ANCOVA.

Hello Wendy Baker Smemoe

Multiple T Tests analysis can help you.

See the link below

https://www.graphpad.com/guides/prism/latest/statistics/stat_how_to_multiple_t_tests.htm

Abolfazl Ghoodjani, I am not a GraphPad user, so pardon my ignorance if I am just misunderstanding the documentation. After reading the page you pointed to, I am left thinking that the "multiple t-test" method returns exactly the same results one would get by using the (single) paired t-test command multiple times. If so, there is nothing resembling the test of interaction that Wendy Baker Smemoe appears to be thinking about.

PS- Are you still at the AECRP? I could not find you on its website (https://www.mcgill.ca/painresearch/).