What are various in-vitro assays that should be performed to evaluate the toxicity of a new excipient for (subcutaneous) insulin?

A new excipient has been developed that enhances the stability of insulin. However, we wish to evaluate the in-vitro toxicity profile before evaluating the toxicity in-vivo. I would like to know...

27 February 2019 2,337 2 View

Does anyone can help me to create PSI_SCRATCH directory for PSI4 program in Ubuntu 18.04?

Hello everyone, I installed everything except last part of the PSI4 program. I tried but, unfortunately I do not have enough terminal commands knowledge. So, it would be very helpful to me if...

04 January 2019 6,320 2 View

What is the best surfactant for oil and water mixing?

I am interesting to make the formulation of neem oil with water. So please give best suitable example of solvent for mixing.

13 September 2018 9,282 2 View

When to add stop solution in indirect ELISA?

In the indirect ELISA being performed, when should the stop solution (H2SO4) be added after the addition of substrate (TMB)...? It has been observed that adding H2SO4 after 2 minutes and 5...

04 March 2018 9,265 6 View

What is Attenuated Total Reflectance (ATR)? Can ATR help us the understand the adsorption of molecules on the surface of alloy?

can ATR help us the understand the adsorption of molecules on the surface of alloy?

26 February 2018 1,700 1 View

Can we communicate an article to more than one journal at the same time?

Suppose, I have already communicated a paper to a good journal, But the editor is taking a longer period of time to review process so can I communicate the same paper to any other journal .

04 December 2017 4,731 9 View

Can LCMS help to identify the major phytochemical constituents present in a plant extract?

Can LCMS help to verify the presence of different phytochemical constitutes in the plant extract? Because their may be many phytochemical compounds present in the plant extract, can we verify most...

30 November 2017 4,471 7 View

Can anyone tell me how to obtain the model equation using weights and bias in ANN?

I am trying to obtain the response model for resistance spot welding.I have used TANSIG function for hidden layer and PURELIN function for output layer to obtain weight and bias. Now I need to...

28 July 2016 9,707 6 View

Usage of ICT tools

A teacher should treat himself/herself as a facilitator in today's classes and it can be easily achieved by quizziz.com, kahoot and menti.com etc. Integration of these tools really help us in...

01 January 1970 957 4 View

OpenMPI error in ORCA calculation

Dear computational chemists, I submitted geometry optimization job to the ORCA using ORCA OpenMPI 3.1.4 and I got following error when I ran input file with PAL2, Process recieved...

01 January 1970 9,097 2 View

Polymer composites suddenly solidifies?

I am making polymer composite by solvent mixing method. When I am trying to add filler solution in polymer solution it quickly get solidified. How to make them then uinform? It doesn't give time...

03 March 2021 7,540 4 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

How to polymerize TEOS?

I want to polymerize TEOS on a surface. I know that NH4OH is a preferred catalyst and an alcoholic solvent should be used .But I can not find certain amounts of each material to use. Does any one...

02 March 2021 1,404 6 View

How can extract ciprofloxacin hydrochloride disolve in water er to organic solvent such as dichloromethan or any other solvent?

I need a procedure to extract the ciprofloxacin hydrochloride from aqueous solution by using dichloromethane in detail,. I thank you very much.

01 March 2021 4,306 1 View

How to separate water from glycerol solvent in a solvent recovery vacuum distillation column?

I am currently doing my third year design project. I have been assigned to design a glycerol recovery column in vinyl acetate monomer production. The process unit before the recovery column is an...

01 March 2021 9,525 4 View

How to make fractions of chloroform extract of plant, using seperating funnel?

28 February 2021 8,466 2 View

Why am i not getting solid after reacting APTES with salicylaldehyde?

The reaction of APTES with salicylaldehyde in ethanol leads to the formation of imine compound yellow solid which is mention in literature, but I am not getting yellow solid I don't know why? when...

28 February 2021 2,955 2 View

can I treat waste water containing solvents and alcohol with electrocoagulation?

there are solvents and alcohol in the waste water of a factory that produces disinfectants. Increasing this waste water requires very serious operations. Can I treat this waste water with...

27 February 2021 2,609 3 View

How the wettability of rock sample can be changed by ageing in pure hydrocarbon oils only?

I want to do wettability analysis of hydrocarbon oil (octane)/rock/surfactant solution system. but to do the analysis first I have to make rock surface oil-wet. Since hydrocarbon oil does not have...

27 February 2021 5,383 3 View

How to replicate the well conditions of a crystal hit with 20%(w/v) isopropanol?

I had a crystal hit in a well with 0.1M HEPEs pH 7.5, 10%(w/v) PEG 4000, and 20%(w/v) isopropanol. Why is isopropanol in w/v here if it's just solvent? How do I recreate this well condition?

25 February 2021 9,761 1 View