Dear Doctor, VEGF primarily is important for angiogenesis and particularly in tooth movement, it leads to enhancement of  osteoclast recruitment, thus accelerating tooth movement. But however there are animal study models that support this finding, I am not aware of human studies where they have been assessed in body fluids. It still is potential biomarker for tooth movement

Hi Dr. Prasad,

Here are some key references for your question.

PMID:23611723

PMID:23129289

PMID:22665981 (This paper summarizes Cytokines and VEGF induction in orthodontic movement.)

VEGF though investigated in animal studies, has not been investigated sufficiently for human applications yet.

Very true- Thank you so much dear Dr. Shivam for your input