What is the role of Phorbol 12-myristate 13-acetate (PMA) in the induction of Complement Receptor 3 (CR3) or CD11b/CD18 and CR4 or CD11c/CD18?

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James Drummond

I believe PMA is a diacyl glycerol analog. It is involved in similar pathways to DAG

Saleh Alkarim

Hello

i agree with James Drummond , kindly look at links here

Good Luck

https://www.google.com.sa/search?q=role+of+Phorbol+12-myristate+13-acetate+(PMA)+in+the+induction+of+Complement+Receptor+3+(CR3)+or+CD11b%2FCD18+and+CR4+or+CD11c%2FCD18&oq=role+of+Phorbol+12-myristate+13-acetate+(PMA)+in+the+induction+of+Complement+Receptor+3+(CR3)+or+CD11b%2FCD18+and+CR4+or+CD11c%2FCD18&aqs=chrome..69i57.2195j0j8&sourceid=chrome&ie=UTF-8

https://www.ncbi.nlm.nih.gov/pubmed/10529599