To perform a quality assessment of included studies for an meta analysis consist of retrospective studies . There are many tools as Cochrane items, the most reliable tools, but if we apply this tools for retrospective studies, the end result will be a high risk of bias. Since, retrospective studies formulate a main literature bases in some topic. Thus we have to do an evidence base decision paper regarding this topic according to the available literature even it were retrospective in nature.

Are there a specific tools to determine a risk of bias within retrospective studies?

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