I think, one of the most important (not sure the most) is nutritional deficiencies

Dear Dr. Hoseinifar,

Thanks for your attention and comment.

Which element and what about occurrence process and its pathogenicity?

Meanwhile, nutritional factors could be one of them. What do you think about other important factors?

One of the factors should be genetic defect from inbreeding whereby natural shuffling of genes among individuals tends to be disrupted with unhealthy genes. Another possible reason is  injury during husbandry procedures such as high current flow of water. This i have observed while we were raising catfish fingerlings in our fish farm.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC339614/

Dear Thlama,

Thank you so much for your comment and valued article.

In fact all three type of Spinal cord deformity consist of kyphosis, scoliosis, and lordosis would be available in Sturgeon reared farms.

in many cases vitamin C deficiency could be most important in nutritional factors.

http://www.ncbi.nlm.nih.gov/pubmed/660305/

What do you think about other important factors such as infectious agents?

Dear colleagues,

Regarding to your interest about proposed topic (Spinal deformities), I found valued article for more information in PMC site as follows:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631747/

Hopefully it would be useful for our interested colleagues.

Hello Jalil Zorriehzahra

please check this attachment and it is very informative regarding Sturgeon fish

regards

Dear Nirmala,

Thank you so much for your valued mannual.

It seems very useful and informative.

Thanks again

Kindly regards

Dear Jalil,

Fertilized fry trauma can be also initiator and can be aggravated by nutritional deficiency. At least in trouts this can be seen or is a follow up  of improper handling of the eggs. Interesting will be the association of the spine deformations with the morphology of the scutes (scales). There one can most likely see whether there is nutritional or congenital cause. 

Best regards,

Ivan

Dear Dr.zorriehzahra

It can be caused by various factors; such as bad condition of transportaion in early age, malnutrition (mineral deficiency), high stocking densities, thermal shock and some of  the pathogens like VNN. 

Best wishes

Fatemeh Hassantabar

Dear Dr. Hassantabar,

Thanks for your valued response.

Regarding to your answer about malnutrition (mineral deficiency), which mineral could be more important?

Kindly regards

You don't say how much of a problem it is.  The number affected in a cohort can give you a good indication of the cause. When the proportion of affected fish is high, it is most often a diet issue and is often associated with other problems. In warm conditions commercial diets do not keep well, and often vitamins are added to excess to counter the developing rancidity of the fats, but if stored too long the vitamins become ineffective and the fish suffer a vitamin deficiency. Electric currents are a common cause (lack of proper earthing of equipment causing electric shocks to fish).  There are often a small proportion of the fish which are deformed for genetic and egg damage issues and these are usually culled. Shocking of eggs (for whatever reason) can induce spinal deformity. Parasitic diseases can sometimes cause spinal deformities but they are not commonly encountered.

Hi dear Dr. Zorriehzahra. in addition to the daily diet, vitamins and genetic the stocking density in surgeon is very important  

When I view the pic I notice a red spot on the fish indicating disease issue.  Has this been diagnosed?  Also, the tank the fish is in the pic is way too small for the fish, is the deformity recent?

Dear Cindy,

Thanks for your answer. You are right  and it could be secondary infection that may be caused by some opportunist pathogens like Aeromonas hydrophila that could be found easily in mentioned environment.

Regarding to mentioned Tank it belong to our Laboratory that was temporary and used in examination period.

Vitamin C deficiency is usually the major cause of such condition. However, it is always safe to rule out any infective disease which looks possible in this case. If you get a negative, then you should definitely go for Vitamin C estimation of the feed.