max. conc. should be solubility limit to avoid covering with crystals, 0.1% would be o.k., however, sufficient would be slightly above cmc.

Dear Tanvi,

Sodium dodecyl sulfate (SDS), Sodium lauryl sulfate (SLS) 0.18–0.23% [1–3].

1. Mihali C, Oprea G, Cical E. Determination of critical micelar concentration of anionic surfactants using

surfactants—sensible electrodes. Chem Bull “Politehnica” Univ (Timişoara). 2008; 53(67):1–2.

2. Stippler ES. Biorelevant dissolution test methods to assess bioequivalence of drug products [PhD

dissertation]. Frankfurt: Johann Wolfgang Goethe University; 2004.

3. Koga K, Kusawake Y, Ito Y, Sugioka N, Shibata N, Takeda K. Enhancing mechanism of Labrasol on intestinal

membrane permeability of the hydrophilic drug gentamicin sulfate. Eur J Pharm Biopharm. 2006; 64(1):82–91.

See attached file.

Hoping this will be helpful,

Rafik

Thank you Mr. Sobisch and Mr. Karaman!