If you had a grade four extravasation injury from an infusion of THAM in a neonates hand , what would be the most appropriate emergency treatment?
Would this emergency treatment reduce the morbidity associated with the injury?
Hi James, these are the most useful papers I found: the Neonatal Intravenous Extravasation Injury: Prevention and Treatment is from the NHS and mentions THAM, but not tx specifically. The other paper (both papers attached) may also be useful. Both are examples of good evidence based research that you could look at for practice.
Hyauronidase or wydase have been used for this purpose and mentioned in the literature. I have several experience myself but the drug is in shortage.
Removal of extravasated drug from tissues in early period by saline washout via small incisions as mentioned in the literature
very very interesting
in our hospital we have reduced the extravasation using PICs to blister substances especially in premature and extremely premature
thanks Victoria
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