What is the main difference between the AUC and AUAC values used in virtual screening?

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Sergey Shityakov

Therefore, the AUAC value provided a lesser number in docking experiments due to the saturation effects? However, the all values are above a 0.5 random parameter indicating statistically appropriate results.

Dear Paul, could you be so kind to take a critical look at the manuscript regarding to virtual screening? Appreciate your help and assistance.