Many in-vitro anticancer, mechanistic studies have been reported to use Tamoxifen (TAM) as a positive control for Estrogen Receptor + (ER+) breast cancer cells like MCF-7. But what will be an ideal positive control for in-vitro mechanistic studies involving triple negative breast cancer cells like MDA-MB-231 in ?
Zahra Sepehri
Hi Aniket
im working now on MDA-MB-231 cells And their metastatic cell lines. In my project we decide about the positive control based on each target that we are looking for, separately.
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Shyam Nyati
he positive control should be decided based on what you want to achive in the project. General agents commonly used are docetaxal,
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