It is known that the realistic number of effective replications of any DNA from the birth to the death is about 50 for many different organisms (for example, E.L Scheider, H. Stemberg, et al, Mechanisms of Aging and Development, 9, 1979, 313; Victor Ostrovskii and Elena Kadyshevich, Global Journal of Science Frontier Research; Physics and Space Sciences, 12, issue 6, version 1.0, 2012, 1). Which ways are there to increase the number of DNA replications or increase the time interval between replications?
I like the question and we all like to know the answer. To my knowledge mild diet restriction can prolong life in some species. Both AMPK activation and autophagy increase with mild starvation and may contribute to the effect. But, I do hope to learn from everybody.
Dear Ru-Jeng Teng,
I will try to stimulate the discussion by the proposal for giving attention to the approach to this problem solution published in the paper "Life Origination Hydrate Hypothesis (LOH-Hypothesis): original approach to solution of the problem" available in the ResearchGate and for free in Global Journal of Science Frontier Research (A), vol. 12, issue VI, version. 1, 1-36, 2012.
The problem of prolongation of life and of optimal nutrients is considered in pages 27-29.
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