In fact, there are two main disadvantages of DSI (Hardware requirements are high and acquisition time is comparatively long). What I mean in my question that I look for something more specific, because I'd like to work in this area by applying one of metaheuristic approaches with DSI tractography problem
Diffusion spectrum imaging (DSI) tries to overcome this serious limitation with various methods. You can read more if you are interested in the details of these methods
https://www.quora.com/What-is-the-difference-between-Diffusion-spectrum-magnetic-resonance-imaging-DSI-and-diffusion-tensor-imaging
http://www.sciencedirect.com/science/article/pii/S105381190800253X
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005101
http://www.ncbi.nlm.nih.gov/pubmed/18495497
http://www.the-scientist.com/?articles.view/articleNo/41266/title/White-s-the-Matter/
Dr.Ghulam Sarwar Shaikh ....... Thank you very much for your efforts
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