I have a genotype data of over 1500 SNPs spanning over the entire human genome (N=100). I would like to analyse the SNP-SNP interaction of these markers in my study population. I would like to know which tools would be most appropriate based on my study design?
Any suggestion would be of great help and shall be highly appreciated. Thanks in advance.
I am not an expert of SNP analysis and not a fan either. I think SNP studies are a bit too overrated. But that would not change anything and my opinion does not count.
However, this was an interesting paper to read and it describes the process in quiet a detail, please have a look.
Cao, X., Liu, J., Guo, M. et al. HiSSI: high-order SNP-SNP interactions detection based on efficient significant pattern and differential evolution. BMC Med Genomics 12, 139 (2019). https://doi.org/10.1186/s12920-019-0584-6
- Badges
- Science topic
- Similar topics
- Teacher Education
- School