Several pieces of research model this self-interference (SI) using different random distributions like Rician, Nakagami-m, Rayleigh, etc. The cancellation techniques allow the SI suppression up to a certain level and only a very small amount of residual SI remains. According to my understanding, due to the presence of transmitting and receiving antennas at the same node the LOS component will dominate that can be canceled using cancellation techniques. But due to multipath effects, the residual SI component is very small.
It depends on what you are analyzing. Depending upon your objective function you can model it, however, for broad and general modeling you can model it as a sum of both LOS and NLOS components.
Maybe a good model would be Nakagami-m, since it can model both LOS and nLOS. I have used this model in Article Energy Detection in Full-Duplex Systems with Residual RF Imp...
Nakagami-m is generalized, however, recently Rice university researchers proposed through experiments the Rice distribution.
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