What is the best method to convert chloroactic acid (ClCH2COOH) into chloroacetic anhydride (ClCH2CO-O-CO-CH2Cl)?
I am agree with Theo Nikiforov ,even acid chloride will be the best method for the synthesis of anhydride in my view. You can use SOCl2 or Oxalyl chloride(mild condition) for making acid chloride.
thanks for the advice, I will try use acid chloride instead.
I need a small amount of 4-aldehyde-3-phenylsydnone or 4-aldehyde-3-(4-methoxyphenyl)sydnone. Any suggestion for a supplier.
05 June 2015 7,397 0 View
Is there anyone who tried to prepare 4-acetyl-3-phenyl sydnone using 1,3-Dibromo-5,5-dimethylhydantoin (DBH) as a catalyst as described by Azarifar et al, 2007. I have tried it on various 3-phenyl...
31 December 2014 8,179 14 View
If both dependent and independent variables are categorical, do I have to check for confounding? And what test should I use to find the confounding variables using SPSS?
04 May 2014 6,045 10 View
For further information please see the attached figure.
03 April 2014 6,757 3 View
Drug Discovery and Development Natural products Nutraceutical and Cosmeceutical Veterinary Pharmaceuticals Pre-clinical and Clinical Studies Supply chain Waste Management Marketing &...
11 December 2013 9,188 0 View
.
10 November 2013 577 5 View
What is the minimum purity of an isolated/synthesized compound to get a reliable IR/NMR/MS spectra?
09 October 2013 4,318 12 View
What species of candida give white colonies on ChromAgar candida?
09 October 2013 5,383 8 View
When running the Legacy Dialogs for two independent samples using SPSS, there are many tests like Mann-Whitney U test, Moses extreme reactions and Wald-Wolfowitz runs. What is the difference...
05 June 2013 5,814 5 View
Can we start from 4-chloroaniline?
04 May 2013 7,663 4 View
Approximate concentrations are require in compared with the WHO permissible limts
11 August 2024 2,723 1 View
Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!
11 August 2024 3,770 4 View
Hey there, As a synthetic chemist delving into theoretical calculations for my imidazolium-based organic molecules, I would greatly appreciate any guidance on the appropriate input instructions...
09 August 2024 5,444 7 View
I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...
08 August 2024 8,329 0 View
Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.
07 August 2024 8,782 3 View
I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?
02 August 2024 7,186 6 View
Hi everyone, I'd like to better separate two close peaks coming from a bioconversion sample, I'm currently using a C18 KromaPhase 4,6mm Ø.I. SCHARLAU, particle size (µm): 10, pore size (Å): 100,...
30 July 2024 435 3 View
I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...
30 July 2024 6,420 1 View
Can an analytical method's limit of quantification (LOQ) be outside its linear dynamic range, or is it always required to be within it? Please provide a thorough explanation supported by verified...
29 July 2024 7,198 9 View
I am doing research on wear mechanism of the additive manufactured metal parts under dry condition. Please share the reference to start the analytical modelling of the wear prediction.
29 July 2024 6,115 0 View