I am setting up a study to collect DNA and blood samples. I would like to do various downstream metabolomic & proteomic applications but will not have funding for these measurements until a few years after sample collection. What would be the best collection/storage method for long term metabolomic/proteomic applications? Any advice greatly appreciated!
Hi Philip,
an alternative method but very useful for metabolomics and proteomics approaches are dried blood spots! We tryed that and the compliance and the coverage is comparable even better as usual storage methods like Merin desceribed. It is very simple to collect without a doctor, we used: http://www.whatman.com/DMPK.aspx. However I have no experience to store them over years..
a good overview can you find here: http://www.ncbi.nlm.nih.gov/pubmed/22576654.
requirements are state of the art equipment, because of sensitivity (max. 50-80µl blood are in a circle)!
An expert in metabolomics and sample preparation for large experiments is Warwick Dunn close to you.
http://www.bhamlive3.bham.ac.uk/schools/biosciences/staff/profile.aspx?ReferenceId=53168&Name=dr-warwick-dunn
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