Research published in the Journal of Physiology indicates that ketogenic diets, which are low carbohydrate high fat eating plans that are known to lead to weight loss, may cause an increased risk of Type 2 diabetes in the early stage of the diet. Does anyone know the absolute risk? If you are type II diabetic already what are the consequences?
High fat diet may increase the risk of hypertension and atherosclerosis in patients with diabetes.
Dear Chris,
Maybe the following papers will help you on the subject:
Saslow LR, Daubenmier JJ, Moskowitz JT, Kim S, Murphy EJ, Phinney SD, et al. Twelve-month outcomes of a randomized trial of a moderate-carbohydrate versus very low-carbohydrate diet in overweight adults with type 2 diabetes mellitus or prediabetes. Nutr Diabetes 2017;7(12):304. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865541/pdf/41387_2017_Article_6.pdf
Saslow LR, Mason AE, Kim S, Goldman V, Ploutz-Snyder R, et al. An online intervention comparing a very low-carbohydrate ketogenic diet and lifestyle recommendations versus a plate method diet in overweight individuals with type 2 diabetes: a randomized controlled trial. J Med Internet Res 2017;19(2):e36. https://www.jmir.org/2017/2/e36/
Brouns F. Overweight and diabetes prevention: is a low-carbohydrate-high-fat diet recommendable? Eur J Nutr 2018;57(4):1301-1312. https://link.springer.com/content/pdf/10.1007%2Fs00394-018-1636-y.pdf
Best wishes from Germany,
Martin
The keto diet is a low-carb, high-fat diet plan that causes the body to burn fat instead of carbohydrates — a process known as ketosis. This is said to help with weight loss.
The Journal of Physiology published the research, which said following the diet in its early phases could boost the risk for type 2 diabetes.
The study, which was conducted by ETH Zurich in conjunction with University Children’s Hospital Zurich, involved feeding mice two different types of diets (a ketogenic diet and a high-fat diet, which causes the liver to become resistant to insulin) and then performing standard metabolic tests on them.
Using specialized procedures, the researchers were able to determine the effects of internal sugar production from the animal (mostly the liver) and sugar uptake into tissues (mostly the muscle) during insulin action.It is important to note that the research did not analyze whether the diet employed causes obesity in the long term. The researchers note that the mechanism behind the whole process was undetermined and therefore, “The existence of a shared physiological response between low-carb and regular, high-fat and carb diets that cause insulin resistance in the liver requires further exploration.”
The ketogenic diet may improve blood glucose (sugar) levels while also reducing the need for insulin. However, the diet does come with risks, like fear from diabetic ketoacidosis if the blood glucose level not controlled well, in addition to highe fat leads to hypertention in susceptible patients.
Thanks dear@ Cris Oliver for this valuable question that need more research.
Ketogenic diet which is rich in fat increase vascular complication of diabetes and some researched revealed that it can increase the risk of type 2 DM but more researches are needed in that point.
The ketogenic diet may be a vaible glucose managment option for some people with type 11 diabetes . As ketogenic diet involves different source of energy can lead to some adverse effect like risk of dyslipidemia and possible increase hypoglycemic episodes.