What is Pa and Pi value in medicinal chemistry?

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Byju Ponnana

Pa and Pi value tells the probability of activity.

Pa means probability to be active and Pi means

probability to be inactive..

If Pa > 0.71 you can expect the molecule will show that activity.

For more details you have to study the docking with respective protein

Pragna Thanki

Thank you Byju Ponnana sir.

Dr. Mayur Mohanrao Aitawade

Pa= Pharmacological Active

Pi = Pharmacological Inactive

(Avail PASS online free software) or overlook my "insilico....." publication.