T Its a deposition of soft cellular and fibrous tissue on the bone resulting in weakness & deformity on long bones ,the animal show
a shifting lameness and arching of the back , Local swelling of the lower and alveolar margins of the mandible is followed by soft, symmetrical enlargement of the facial bones, which may become swollen so that they interfere with respiration ,,the case occur due to Vit D deficiency
Osteodystrophia is a metabolic bone disease characterized by increased osteoclastic resorption of bone and replacement by fibrous connective tissue due to prolonged and excessive secretion of a parathyroid hormone in
horses
If the animals are fed a diet rich in cereal or cereal products this secondary nutrional hyperparathyreoidism can develop (bran disease).
Some publications suggest that grasses containing high levels of oxalate can also cause the disease.
Walthall, J. C., & McKenzie, R. A. (1976). Osteodystrophia fibrosa in horses at pasture in Queensland: field and laboratory observations. Australian veterinary journal, 52(1), 11-16
Osteodystrophia fibrosa is a nutritional deficiency disorder due to secondary hyperparathyroidism leading to severe skeletal and soft tissue lesions. This rare disease results from feeding a diet low in calcium, high in phosphorus or with improper calcium: phosphorus ratio of less than 1:1 regardless of whether dietary calcium is supplied at optimal or even excessive levels.
Article A case report of osteodystrophia fibrosa in a horse
Osteodystrophia is a metabolic bone disease characterized by increased osteoclastic resorption of bone and replacement by fibrous connective tissue due to prolonged and excessive secretion of a parathyroid hormone (PTH). ... Hence, the disease in horses is often referred to as "bran disease."
people.upei.ca/lopez/2-bone-metabolic.pdf
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