For example, are metabolically important genes regulated by low concentrations of oxidants (e.g. hydrogen peroxide)?
The task involves predicting a binary outcome in a small data set (sample sizes of 20-70) using many (>100) variables as potential predictors. The main problem is that the number of predictors...
10 November 2015 9,260 11 View
For example, cells were exposed to different concentrations of a toxic chemical. Two types of data were measured: (1) the critical concentration above which no cell growth occurred, (2) for lower...
03 April 2015 5,159 24 View
The data provided are percentiles (median, 75th and 90th) from several histograms. The number of observations comprising each histogram is known. The shape of the data distribution in each...
31 December 2014 7,014 5 View
Suppose a mouse study is being designed which aims to address the question of which dose response shape (e.g. linear, quadratic, exponential, etc) best describes the response to a particular...
04 May 2014 3,157 11 View
Some in vitro data using cancer cell lines has been published, which suggests reprogramming of non-tumorigenic cancer cells to cancer stem cells induced by ionizing radiation. Is there some...
03 April 2014 6,428 1 View
Suppose a mathematical model consisting of a system of differential equations is constructed to describe some biological phenomena. Analytic solutions are not available - only numerical ones. Are...
03 April 2014 551 14 View
For example, suppose a certain method was chosen for power/sample size calculation for a future experiment, with the intent to use the same method to analyze the experimental data. But the...
31 December 2013 5,465 20 View
Among the many available methods, which are the most efficient (i.e. require the smallest sample size for defined alpha and beta) and relatively straightforward to implement?
11 December 2013 9,977 10 View
Suppose there are several treatment groups. Within each group there are exponentially distributed data, i.e. the number of counts is proportional to exp[-A*x^B], where A and B are parameters. What...
09 October 2013 476 56 View
Suppose a non-linear smooth function is fitted to some data (e.g. means and standard errors for cell survival after various radiation doses). What are some useful ways to assess goodness of fit...
08 September 2013 8,064 39 View
I'm trying to find a DNA extraction method for fungi that does not require equipment and heating. Is there anyone who can suggest an alternative option? Thank you
08 August 2024 4,733 2 View
After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...
05 August 2024 9,637 2 View
Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...
05 August 2024 6,247 3 View
Now research fellow used it to prevent fungus in potato,may be potatoes gene effect.
02 August 2024 180 3 View
Please discuss someone told about fungus and allied others.
31 July 2024 3,372 3 View
I created a file with my outgroup and ingroup species using Beauti, ran it in BEAST, viewed it in Tracer, and then used TreeAnnotator to create a file that I imported into RASP. Could someone...
28 July 2024 2,979 1 View
PeptiCloud (www.pepticloud.com) is a bioinformatic platform that allows researchers to organize and share their data for their projects as well as collaborate with others in one place. Through...
28 July 2024 4,762 2 View
Do you know of any online international conferences that offer free discussions? I am looking for examples in the field of molecular ecology and DIY biology.
28 July 2024 6,501 0 View
Now i am working on AM fungi single strain. What are the most effective isolation techniques for obtaining pure cultures of arbuscular mycorrhizal (AM) fungi?? Is there are best approach...
26 July 2024 6,520 1 View
Hello, We found three packages of Illustra™ MicroSpin™ G-25 columns in the cabinet of an unused lab. They are very old but have never been opened. I have never used this kit before, and I couldn't...
25 July 2024 4,927 3 View