My guess is that it boils down to insulin resistance and fluid overload, though perhaps more to the former than the latter.

Good morning Usama Asghar, if you read my paper- MJA, included are variables associated with screening for the aust diabetes screening study.

There are several important publications with the comprehensive current scientific position:

• - DOI: 10.1111/jch.12049
• - DOI: 10.1007/s00467-020-04579-3
• - DOI: 10.1016/j.phrs.2017.05.013
• - DOI: 10.2174/1573402115666190415154603
• - doi: 10.1016/j.mcna.2016.08.008
• Naturally, at the current moment there are not only single theory and explanation, but the problem is a much clear and simple than neighboring topic about diabetes and development of its complications: lesions of the brain, arteries, microcirculation, CKD, heart dysfunction and heart failure. It seems just the intermediate stage of the progression of cardiovascular continuum.