What is correlation of LC50 with binding energy using docking study?

More Hussein Ali Kadhim Kyhoiesh's questions See All

Is it possible to set a breakpoint at a specific DYNAMIC instruction using the GNU Debugger (GDB)?

Using GDB, it is straightforward to debug and monitor a target program by setting a break-point at a specific instruction, since the instruction addresses are known. However, we have two...

24 February 2021 1,598 2 View

Whic Type of Thermal Camera is Good to use in animal research?

Hello dear researchers I want to use a thermal imaging camera to livestock study. I wonder which type to use. If you know or used a good type please comment or insert its online link in...

29 January 2021 4,163 4 View

What are the most practical applications of nano fluid in air conditioning systems ?

explain your idea

01 January 2021 8,593 2 View

Which is the best software in Organic and Perovskite solar cells simulation SILVACO or Fluxim (SETFOS)?

I need to use a new software in Organic and Perovskite solar cell simulation

24 December 2020 2,397 4 View

Please , can the concentration of the drug inside the nanocarriers or nanoparticles be determined using a UV spectrophotometer ?

Please, can the concentration of the drug inside the nanocarriers or nanoparticles be determined using a UV spectrophotometer after getting the calibration curve of the drug alone?

19 December 2020 4,634 5 View

How to correct time series data if there are missing values from the original source?

Some times there are missing values for some years in time series data, how to deal with this problem?

11 December 2020 1,263 3 View

Does the Chinese navigation satellite system (Beidou) become global or still regional?

I know that this system was regional before, thus covering specific areas not alla the global

09 December 2020 3,343 3 View

Do you have the XRD JCDPS of Polycrystalline ZnS?

Hi, I need the JCDPS of polycrystalline ZnS, it would be appreciated if you could help me through this thank you in advance

30 November 2020 3,342 3 View

What are the best kind of mesh to save the running time in 3D trapezoidal cavity ?

explain your idea

24 November 2020 9,036 2 View

Does the freeze-dried change the color of the NCQDs quantum dot?

I have synthesized NCQDs using citric acid and urea as precursors. The powder-color of the quantum dot after the freeze-dried is green; however, the color will change to black as stored at room...

29 October 2020 3,700 3 View

After a reference from Int J Body Compos Res, can any body help?

Hi, I am after the reference below, my library says it cannot obtain a copy either locally or internationally, any help appreciated! Chris Wang ZM, Heshka S, Wielopolski L, Pi-Sunyer FX, Pierson...

03 March 2021 6,193 1 View

Irradiation data for JAPAN?

Hi, Could you help me to get the latest (2019, 2020) solar resource data for a particular site in JAPAN? PV GIS and NSRDB data are not in reach to JAPAN, I'm looking for some other database for...

03 March 2021 961 3 View

RIA. How to measure?

When you use RIA, with a control the unknown sample with antibodies, you bare in mind the binding sites of the antibodies. However you still need to measure labelled antigen (radioactive) and not...

28 February 2021 2,133 3 View

How to calculate Ligand-active site distance in a ligand-protein complex from MD simulation?

I have run a MD simulation of a ligand-protein complex in GROMACS using CHARMM forcefield. Reviewer has asked me to calculate Ligand-activesite distance and binding free energy of ligand with...

27 February 2021 4,703 1 View

Why do the air flow results vary totally when adding scalar in CFD ?

Dear All, We are using Autodesk cfd to calculate the air flow in a single sided naturally ventilated room, where air flow depends only on buoyancy due to temperature difference between inside and...

25 February 2021 9,602 4 View

How to model Supercritical water gasification (SCWG) process in Homer software?

Hi everyone How to model Supercritical water gasification (SCWG) process in Homer software?

25 February 2021 4,075 1 View

Steps to calculate activation energy by coats & redfern method?

I'm a chemistry student and I'm researching the kinetic degradation of mixed plastic waste. I'm having trouble calculating the activation energy by the coats & Redfern method. The data that...

24 February 2021 974 1 View

Is it possible to define biogas as a fuel in the reformer process(scwg) in Homer software?

Hi every one Is it possible to define biogas as a fuel in the reformer process(scwg) in Homer software? Biogas fuel is not available in the options thanks

23 February 2021 6,518 3 View

Are there any candidates for an Einstein's bare cosmological constant?

It is commonly accepted that General Relativity has its own 'bare' cosmological constant that contributes together with the cosmological constant resulting from vacuum energy density for an...

23 February 2021 5,448 8 View

Could the "incoming radiation (net radiation)" values be negative?

Could the "incoming solar radiation" values be negative? What is the difference between "global solar radiation" and "incoming solar radiation"? Which one might be measured negative values?

21 February 2021 7,726 9 View

Debojyoti Pal

Binding energy can only be kind of estimated to dissociation constant type of thing. You can't really compare it to LC50. LC50 can happen at 20% inhibition of a protein, or it can happen at 80% inhibition of a protein. You cannot relate LC50 to binding energy.

Nikolaos Kourkoumelis

Perhaps this could be of help: Article Molecular Docking and Structure Activity Relationship Studie...