The models available in VEGA (www.vegahub.eu/portfolio-item/vega-qsar/) are only trained with bacterial mutagenicity. They have been developed with a data set of about 6 thousand data and using different software tools - including SarPy, SVM, and domain knowledge. The result is only classification, as data are obtained from the AMES test.
For ICH M7, databases with doses should be used instead, either in regression or to build a predictor of multiple classes of concern. We had some work using the Gold database for carcinogenicity.