The journal published by Oguzhan Zengi entitled "The transition from gel separatory serum tubes to lithium heparin gel tubes in the clinical laboratory" aims to assess the viability of replacing serum with plasma samples. The study's lactate dehydrogenase (LDH) measurement conjures discrepancies in values between plasma and serum samples.
The factors to be considered in order to avoid discrepancies in values for LDH measurement include variation in tube brands, plasma contamination with platelets, fragmentation of platelets, and fragmentation of erythrocytes. Platelet residues and lysis in plasma, as well as hemolysis and coagulation in serum, can also have an influence on LDH measurement. Overall, the type of sample, preparation process, and tube selection must all be considered in order to obtain an accurate evaluation and interpretation for your LDH measurement.
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