Hello Deepak, this is clearly an important technical question which is of broad general interest to many other RG members as well. Virtually every organic or inrganic chemist is frequently faced with the problem of how to grow single-crystals of new compounds which are suitable for X-ray diffraction. Quite often this is more an art than just a technique. There are many different ways you can try the crystallization, such as cooling of saturated solutions in suitable solvents of solvent mixtures, layering with anti-solvents, solvent diffusion techniques, sublimation etc.

For some general information about this important issue please have a look at the attached guides to crystallization. These will provide you with an initial overview. I hope this helps. Good luck with your crystallization and best wishes, Frank Edelmann

I agree with going slow, also for organic crystals it can be good to crystallize them at lower temperature if possible. Once I had a compound that gave very poor disordered crystals; I dissolved them in diethyl either and put the solution in a small tube with a rubber septum cap and left it in the freezer for a few weeks, the ether slowly diffused out into the rubber and left very nice crystals with little or no disorder.