You can load a wide range of drug classes onto carbon nanoparticles (CNPs), mesoporous silica nanoparticles (MSNs), and cellulose-based nanoparticles (e.g., CNCs/CNF) due to their high surface area and functionalizable surfaces. Carbon nanoparticles are often used for anticancer drugs such as doxorubicin, paclitaxel, cisplatin, methotrexate, gemcitabine, tamoxifen, and rituximab, either via π–π stacking or covalent/non‑covalent adsorption. Mesoporous silica nanoparticles efficiently load both hydrophobic and hydrophilic small-molecule drugs, including doxorubicin, paclitaxel, camptothecin, topotecan, gemcitabine, and 5‑fluorouracil, often using pore adsorption plus stimulus‑responsive gating strategies . Cellulose-derived nanoparticles (cellulose nanocrystals, nanofibers) have been shown to encapsulate hydrophilic drugs like tetracycline, hydroquinone, procaine, imipramine, curcumin, and doxorubicin (loading efficiencies up to ~80 %) via hydrogen bonding or ionic interactions on abundant hydroxyl/carboxyl surfaces.
Attaching few appropriate references for detail information:
1-Article A Review of Lignocellulosic-Derived Nanoparticles for Drug D...
2-Article Carbon Nanoparticles and Their Biomedical Applications
3-Article Mesoporous Silica Nanoparticles for Co-Delivery of Drugs and...
Carbon, silica, and cellulose nanoparticles can effectively load a wide range of drugs including anticancer agents, antibiotics, and peptides due to their unique surface properties and biocompatibility. Their functionalization allows controlled, targeted, and sustained drug delivery for diverse therapeutic applications.