Big Data has already a moltitude of applications in science. Contemporary research in Physics has provided the first opportunities to adopt Big Data Methods and Technology: have a look at the video below from CERN [#3]. In [#1] you'll find an introduction to the concept of Big Data with a survey of applications to society, business and science. [#2] proposes an interesting provocation on how Big Data might ultimately force the traditional scientific method to change. Hope this helps as an intro.