What if the patient is a 50 year old, with anaemia and a fractured hip? How do these haematology results and immunology results provide us with a diagnosis (see image attached)?
This (female?) patient has macrocytic anemia, probably due to the fractured hip And a lack of vitamin b12. It requires vitamin b 12 injection (subcutanously) and in 6 months time when the anemia has subsided a workup can be obtained: vitamin b 12 regularly? alcohol? etc.
From the results the prediagnosis seems to be megaloblastic anaemia, this can be explained by negative intrinsic factor and below normal range serum vitamin B12 which is partly involved in maturation of the nuclear
Dear Mystic
This patient has macrocytic (megaloblastic) anaemia due to vitamin B12 deficiency. It has nothing to do with her fracture which I suspect is coincidental. Assuming that her diet is satisfactory (not a vegan), your focus should be to exclude malabsorption. She needs detailed gastrointestinal investigations to exclude or confirm atrophic gastritis (gastroscopy), adult onset coeliac disease (small intestinal endoscopy) and other causes of malabsorption. She needs vitamin B12 replacement (parenteral)
Best wishes
Siva
- Badges
- Science topic
- Similar topics
- Biological Science
- Immunology