I'm interested in percutaneously measuring local changes in tissue pH in vivo with and without a therapy. What devices are available for percutaneous pH monitoring in large animals?
For measuring the pH value. digital pH meter is best option.
I am a chemist not a biologist, but I'd expect that there are biocompatible fluorescent pH probes
Please look at the following below links which may help you in your analysis:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166667/pdf/gnl-5-288.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062276/pdf/OAMJMS-6-1235.pdf
Thanks
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