About 30% of Ethiopians are CYP2D6 ultra-rapid metabolizers. The Ethiopian Food, Medicine and Health Care Administration and Control Authority (FMHACA) said it has banned the drug codeine which is used for pain relief, in November 2015. However,codeine is still used in children and adults in this country. The ban and again,the resumption are not based on scientific evidence. To my opinion,codeine could still be a problem on such phenotype group and evidence on the safety should be deeply investigated. 

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