I hope this message finds you Athira V. Anand well! I wanted to reach out regarding your ongoing work with spontaneous nano-emulsification using Labrasol and ethanol. As you Athira V. Anand know, a commonly effective surfactant to co-surfactant (Smix) ratio is 1:1 by weight. However, I understand that the optimal ratio can vary based on the specific formulation and the desired properties of the nanoemulsion.
Since you Athira V. Anand are using Capryol 90 as our oil component, it’s crucial to ensure that the Smix ratio you Athira V. Anand choose leads to a stable and homogenous nanoemulsion. I suggest experimenting with different ratios within the range of 1:1 to 1:2 to find the best balance for your formulation.
Have you Athira V. Anand had a chance to conduct any preliminary experiments with these ratios, or is this your first attempt at optimizing the Smix ratio? I’d love to hear your thoughts and any insights you Athira V. Anand might have from your experiments.