May I know the different types of signaling molecules in bacteria and fungi. Do different bacteria have different signaling molecules. Which are intracellular and intercellular molecules
I've experience only with bacterial quorum sensing and, depending you're dealing with gram-positive or gram-negative bacteria, there are homologies among the biochemical nature of the secreted autoinducers, with the exception of the AI-2 family molecules, which are shared by many bacteria of both type.
In general, you'll deal with Acyl-homoserine lactones, gamma-butyrolactones, oligopeptides and AI-2 molecules. The article by Waters and Bassler (http://dx.doi.org/10.1146/annurev.cellbio.21.012704.131001) contains a nice and complete introduction to the topic.
This may be a good review
http://cid.oxfordjournals.org/content/47/8/1070.full
Dear Uma
The lux-type quorum-sensing system is the archetypal and preeminent mechanism for species-specific communication in gram-negative bacteria,,
Intercellular communication is also used by gram-positive pathogens to control virulence. Rather than using AHL or quinolone-based signaling molecules, cell communication in gram-positive bacteria is based on the production and detection of modified oligopeptides called autoinducing peptides (AIPs)
Communication among microorganisms is mediated by secretion named quorum sensing.
quorum sensing regulate biofilm formation and DNA exchanging and other phenomena, Gram-negative bacteria use acyl-homoserine lactone while gram-positive bacteria use oligopeptides ( 5 to 17 amino acid ).
All quorum-sensing systems utilize small, secreted signaling molecules
known as autoinducers (AIs) that are of three categories: acylated homoserine lactones (AHLs), used by Gram-negative bacteria (also sometimes referred
to as autoinducer-1 [AI-1]); peptide signals, used by Gram-positive
bacteria; and autoinducer-2 (AI-2), used by both Gram-negative
and Gram-positive bacteria. There are also other quorum sensing
signals that go beyond these classes, including
Pseudomonas quinolone signal (PQS), diffusible signal factor
(DSF), and autoinducer-3 (AI-3), and new molecules will undoubtedly
be discovered as the study of quorum sensing expands
to species of bacteria yet to be investigated.
In addition to AHL, AI-2, and DSF , the following database lists DKPs (Diketopiperazines) and HAQs (4-hydroxy-2-alkylquinolines)(, and "others") as categories of signaling molecules. You can search the database by organism, too.
http://bioinfo.imtech.res.in/manojk/sigmol/uniq_QSSMs.php
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