Well. It deals with biocompatibility and degradability of the substance in organism. Both factors depend on chemical composition and its affinity with that of natural compounds. The sweeteners with the structure, similar to natural analogues do possess a non-zero energetic value.
Saccharin (E954), for example, is a purely synthetic sweetener (a sulfanilamide compound), stable in the organism. So, the saccharin-containing food is even used by people with diabetes.Other example of a purely synthetic sweetener without energetic value is acesulfame (E950).
At the other hand, aspartame (E951) is a dipeptide derivative. It possesses an energetic value, but only one pill is enough to make the pharmaceutical formulation "sweet". So, while used in normal quantities, its energetic value may be negligible.
Nevertheless, it degrades in the organism, yielding phenylalanine, which excess in organism may provoke side effects. Other degradation products may be aspartic acid and methanol. Its use is controversial.
Conclusion. The biocompatible sweeteners, used in pharmaceutical industries possess energetic value.
Well. It deals with biocompatibility and degradability of the substance in organism. Both factors depend on chemical composition and its affinity with that of natural compounds. The sweeteners with the structure, similar to natural analogues do possess a non-zero energetic value.
Saccharin (E954), for example, is a purely synthetic sweetener (a sulfanilamide compound), stable in the organism. So, the saccharin-containing food is even used by people with diabetes.Other example of a purely synthetic sweetener without energetic value is acesulfame (E950).
At the other hand, aspartame (E951) is a dipeptide derivative. It possesses an energetic value, but only one pill is enough to make the pharmaceutical formulation "sweet". So, while used in normal quantities, its energetic value may be negligible.
Nevertheless, it degrades in the organism, yielding phenylalanine, which excess in organism may provoke side effects. Other degradation products may be aspartic acid and methanol. Its use is controversial.
Conclusion. The biocompatible sweeteners, used in pharmaceutical industries possess energetic value.
It´s important to mention also some chemically modified natural sweeteners, like sucralose (sucrose, modified by chlorine atoms) and also steviol glicosides, that contain stabilizing fragments. They are non-caloric, as they contain the stabilizing groups.
Here are some commonly uses non-nutritive sweetener compounds: Acesulfame K, Sucralose, Neotame, Sodium Cyclamate, Saccharin etc.
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