I work on oral cancer cells to test the effect of cytotoxic drugs, and every time I see abnormal shapes under a phase contrast microscope and light microscope after staining with trypan blue. They were observed after 24 and 72 hours; I found them abundant after 72 hrs and less in non-cancer cells. For information, I found them once in the control group of the cancer cell line. what are the possible ways to get rid of them?