Usualy nephroprotective drugs of plants orgin were evaluted in nephrotoxicity animal model. But CKD secondary to HTN and DM is also common. What are the method to develop these animal model in a short duration
In Expermental work
1_Urine output and analysis of urine
2_ Tail blood sample for kidney function and oxidative markers
3_ Measure the blood pressure
I think it will help
I hope these researchgate links will help
Article Renal protective effect of SGLT2 inhibitor Dapagliflozin alo...
Article Aqueous Extract of Thymus Vulgaris-induced Prevention of Kid...
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