I am not sure what you mean by 'green synthesis'. This is a term that has been used to mean any process of sythesis that is done in a more environmentally friendly manner than other industrial alternatives, often involving water in place of inorganic solvents. We have recently written a couple of papers that explore biotemplating and biomimetics as green synthesis alternatives for nanoparticle synthesis:

JMC - http://pubs.rsc.org/en/content/articlelanding/2012/jm/c2jm31620j

Chem Eur J - http://onlinelibrary.wiley.com/doi/10.1002/chem.201300721/abstract

If this type of method is what you mean by green synthesis, the advantages are that the chemicals invovled are less toxic to the environment than conventional systems, as aqueous reagents, low temperatures and ambient pressures are used to synthesise the particles. However, it is often slower than traditional routes and the control of particle size may be less stringent. If this is not what you mean by green synthesis, can you add more detail about what processes you specifically mean in your question?

Here is one article for this:

http://www.ncbi.nlm.nih.gov/pubmed/21696293

You may wish to read the articles:

The answers by J Galloway and G S Dhillon are appropriate for the term "Green Synthesis".

Dear Johanna Galloway

I mentioned "green synthesis" based on the following articles.

http://www.sciencedirect.com/science/article/pii/S1359511312001766

http://www.sciencedirect.com/science/article/pii/S1359511311002510

http://www.sciencedirect.com/science/article/pii/S0926669013000460

http://www.sciencedirect.com/science/article/pii/S0926669013004779

They have mentioned that the functional group of phytoconstituents attached with the synthesized nanoparticles (FTIR analysis). Even some of other articles gave full evidence that the nanoparticle's attachment in a specific atom of a particular drug. The attachment of nanoparticles with a particular drug during the synthesis process have good biological activity. How it differs from nanocoating for drug delivery? Is this green synthesis better than nanocoating?

I suppose the only way to tell if one method is better than another is to do an experiment to determine which has the better efficacy and/or toxicity when delivering the same drugs. It may be that one method may be better for some drugs than others in this respect.

Thank you

I provide you with a comprehensive list of publications that provide you with the concept of making nanoparticles using benign anti-oxidants and how they can be utilized in sustainable fashion in catalytic processes.

On the top is the book we recently edited. You can ask for specific article as they originate from my laboratory.

Start from the bottom of teh list, where the concept originally started and grew:

Book: Sustainable Prep. of Metal Nanoparticles: Methods & Applications-RSC (2013)

Nano-Magnetite Support in Sustainable Methodologies.Chem Soc. Rev. 42, 3317 (2013)

Green Synth. Nano (Au,Pt,Pd) with Glycerol/MW:ACS Sustain.Chem.Eng.,1,810 (2013)

Ag Nano-Effect Intestinal & Brain Endoth. Cells:ACS Sustain. Chem. Eng.,1,753 (2013) Toxicological studies

Greener Tech-Ag Nano-Plant Extracts, Enzymes:ACS Sustain. Chem. Eng.,1,703 (2013)

Beet Juice-Induced Green Synthesis Plasmonic AgCl/Ag:ChemSusChem, 5, 2435 (2012)

Beet Juice & MW-Assisted Synth. Nanometals (Pd,Pt,Au,Ag): RSC Adv.2,10283 (2012)

Green Nano & the Sustainable Applications: Curr. Opin. Chem. Eng. 1, 123-128 (2011)

Membranes-Enzyme Cat.&Green Synth of Nanoparticles:ChemSusChem,4,1773 (2011).

Synth of Fe,Fe/Pd Nano Memb. Degradation chlorinated Organics:J.Memb. Sci.,379, 131 (2011)

MW Green Synth. Ag Nano. Nadagouda, Speth, Varma: Acc. Chem. Res., 44 , 469 (2011).

Mag. Sep. Nanoferrite-Anchored Glutathione: MW Aq. Coupling of Arylboronic Acids. R.Luque, B.Baruwati, R. Varma: Green Chem. 12, 1540 (2010)-Cover Page Article

Green Chemistry by Nano-Catalysis. Polshettiwar,Varma: Green Chem., 12, 743 (2010).

Synth., Charact. & Biocomp. of “Green” Synth. Ag Nano Using Tea Polyphenols. Moulton, Stolle, Nadagouda, Kunzelman, Hussain, Varma: Nanoscale, 2, 763 (2010).

Nano-Organocatalyst:Magnet. Retriv. Ferrite-Anchored GlutathioneMW Paal-Knorr, Aza-Michael and & Pyrazole Synth. Polshettiwar, Varma: Tetrahedron, 66, 1091 (2010).

In Vitro Biocompatibility of Nanoscale Fe (NZVI) Synthesized Using Tea Polyphenols. Nadagouda, Castle, Murdock, Hussain, Varma: Green Chem., 12, 114 (2010)-Hot article.

High Value Products from Waste: Grape Pomace Extract-A 3-in-1 Package for the Synthesis of Metal Nanoparticles. B. Baruwati, R. Varma: ChemSusChem, 2, 1041 (2009).

Green Synthesis of Au Nanostructures at Room Temp. Using Biodegradable Plant Surfactants. Nadagouda, Hoag, J. B. Collins, Varma: Cryst. Grow. & Des., 9, 4979 (2009).

Glutathione in Green Synth. of Ag Nano in Water MW’s: Green Chem., 11, 926 (2009)

Mag. Nano-Supp. Glutathione: Sustainable Organocatalyst: Chem. Comm. 1837 (2009)

Self Assembly Metal Oxides in 3-Dimen.Nano:Synth. & Applic:ACS Nano,3,728 (2009)

Pd Nanoparticles: Synth. Using Vit. B1 and Application in Carbon-Carbon Coupling Reactions. M. Nadagouda, V. Polshettiwar, R.S. Varma: J. Mater. Chem. 19, 2026 (2009)

Synth. & Applic. of Micro-Pine Structured Nano-Cat.: Chem. Commun., 6318 (2008).

Green Synthesis of Silver and Palladium Nanoparticles at Room Temperature Using Coffee and Tea Extract. M. N. Nadagouda, R.S. Varma: Green Chem., 10, 859 (2008).

MW-assisted Shape Controlled Bulk Synthesis of Ag and Fe Nanorods in PEG Solutions. M. N. Nadagouda, R.S. Varma: Crystal Growth & Design, 8, 291 (2008).

Green Synth. of Ag and Pd Nanospheres, Wires & Rods Using Vit. B2: Cat. Polym. of Aniline & Pyrrole. Nadagouda, Varma: J. Nanomater, doi:10.1155/2008/782358.

Green Synth.- using Vit. C-Core (Fe,Cu)-Shell (Au,Pt,) Nano:Crys. Grow.&Des.7, 2582 (2007)

Cellulose/Metal Biodegradable . Nanocomps. Nadagouda, Varma: Biomacromol., 8, 2762 (2007)

MW Shape-Sel. Synth. Nanocrystals & Catalytic. Prop-using sugars: Crystal Growth & Des. 7, 686 (2007)

MW Combustion Synth of Spongy Metal Oxides: J. Smart Mater. Struc, 15, 1260 (2006)

Green & controlled Synth. of Au and Pt Nano. Using Vit. B2: Density-assisted Self-assem. of Nanospheres, Wires & Rods. Nadagouda, Varma: Green Chem., 8, 516 (2006)

Dear Prof. Rajender Varma

Thanks for your answer.

I don't have the internet access of these articles. In specific, I am interested in the following articles.

1. In Vitro Biocompatibility of Nanoscale Fe (NZVI) Synthesized Using Tea Polyphenols. Nadagouda, Castle, Murdock, Hussain, Varma: Green Chem., 12, 114 (2010)

2. Synthesis of Fe,Fe/Pd Nano Memb. Degradation chlorinated Organics:J.Memb. SCI., 379, 131 (2011)

3. Glutathione in Green Synth. of Ag Nano in Water MW’s: Green Chem., 11, 926 (2009)

4. Nano-Magnetite Support in Sustainable Methodologies.Chem Soc. Rev. 42, 3317 (2013)

Kindly help me to know the importance of green synthesis.

Can we use this green synthesized nanoparticles for therapeutic purpose (i.e.Cancer, Diabetes)?

Send me your e-mail and i will send you these as df files

Thank you very much for your reply

My Mail ID: [email protected]

Once again thank you sir

Professor Varma

Would you be so kind to send me the paper: Nano-Magnetite Support in Sustainable Methodologies.Chem Soc. Rev. 42, 3317 (2013)?

[email protected]

Thank you very much, and thanks to Rajaram for an interesting topic.

Dear Prof. Varma,

Now i have started the works on synthesis of nano-materials as catalyst for organic transformations. Your listed articles may help me lot to understand the concepts. Kindly send your papers to my id [email protected].

Thank you sir.

Yes, When we use bio extracts as reducing or oxidizing agents it is most useful for drugs than chemical products to avoid toxicity.

Dear sir Rajender S Vaarma kindly email me this literature. I will be highly thankful.

[email protected]

Thanks

Can you please specify the articles as I have in hundreds?

You can see details at Google scholar or Research Gate links below:

Google Scholar: https://scholar.google.com/citations?user=kzbCKOQAAAAJ&hl=en

Research Gate: https://www.researchgate.net/profile/Rajender_Varma/info