Genetic adaptation processes of bacteria are key to its survival In challenging environment
http://link.springer.com/article/10.1134%2FS1022795413010110
The microbes behave differentially towards to different class of toxic substances. The toxic substances may be either organic and inorganic in nature. The interaction of these toxic subatances triggers the expression of defence mechanism in the microbes, which leads to the microbes to overcome the toxicity. The persistance stimulation of toxic resistance in microbes developes constitutive genomic expression of defence mechanisms, where the toxic substances are altered to less toxic via enzymatic actions.
Adapt and resist: how microorganisms deal with deadly metals
http://www.nature.com/nrmicro/journal/v11/n6/box/nrmicro3028_BX2.html
How Silver kills bacteria finally revealed.The use of silver in medicine is as old as medicine it self but how it works has been a mystery ever since.Now, a team led by James Collins, a biomedical engineer at Boston University in Massachusetts, has described how silver can disrupt bacteria, and shown that the ancient treatment could help to deal with the thoroughly modern scourge of antibiotic resistance.
http://www.bullionstreet.com/news/how-silver-kills-bacteria-finally-revealed/5042
Microorganisms in the environment can often adapt to use xenobiotic chemicals as novel growth and energy substrates. Specialized enzyme systems and metabolic pathways for the degradation of man-made compounds such as chlorobiphenyls and chlorobenzenes have been found in microorganisms isolated from geographically separated areas of the world.
http://mmbr.asm.org/content/56/4/677.abstract
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