Hello Clemens, 

Thanks for your answer, I have indeed looked at the ASAP experiments and am pretty fascinated by them. I am indeed running on a Bruker instrument, so knowing the pulse sequences for sf and b_ are very helpful as well.

What are the reasons that these are applied mainly to proteins? I have noticed a number of selective experiments aimed at acquiring signals only for the peptide backbone, but the principal should still work when applied to small molecules, or am I getting these confused with other acquisitions? Also, after reviewing the pulse sequences we have, I am noticing that the majority of pulse sequences (b_) are 3D, which is a wonderful use of the time savings. 

Do Bruker instruments have an ASAP pulse sequence in the instrument library, or is this an example of a pulse sequence that I should obtain from the author? 

 Once again, Thank you very much!

I am super interested in seeing if this works for our application. It seems like quite an advancement, and if the sensitivity loss is acceptable, I am hopeful we will adopt it. 

Thanks for all your help,

Joseph