What are the factors to be considered while performing Molecular docking analysis ? what should be mentioed in result interpretation part ?

More Muthusaravanan Sivaramakrishnan's questions See All

How do I create a custom function for shrinking and perturbing model weights in Keras?

I am referring to this study https://proceedings.neurips.cc/paper/2020/file/288cd2567953f06e460a33951f55daaf-Paper.pdf entitled "On Warm-Starting Neural Network Training". Here, the authors...

24 January 2023 921 1 View

Why the structural similarity index measure decreases with decreasing image resolution?

I computed the structural similarity index (SSIM) value between a ground truth mask and its corresponding predicted mask in an image segmentation task using a UNet model. Both the ground truth and...

12 January 2023 7,403 2 View

Is there any good free app to make concept maps for the Literature review or to present conceptual framework theoretically?

How to draw concepts maps while writing thesis .

05 July 2022 4,721 3 View

Is there any software which would write the references in APA style 7th Edition?

Are there any software's that would help me enhance the quality of writing the different chapters?

29 May 2022 1,403 3 View

How to interpret calibration curves in terms of class imbalance?

I am training a deep learning model toward a image classification task. The VGG-16 model is trained individually on two different training sets with varying degrees of data imbalance. Set-1 had...

29 July 2021 2,946 3 View

Why there is no difference in calibration performance at its optimum operating threshold?

I trained a VGG-16 model on a highly imbalanced dataset where the positive samples (class-1) were only 20% of the negative samples (class-0) ( # positive samples: 100 and # negative samples: 500)....

29 July 2021 6,361 0 View

Does calibration impact performance in a model trained with balanced dataset?

I have trained a VGG-16 model toward a binary classification task. The model was trained on equal numbers of abnormal and normal images (n=2000). Literature studies demonstrate that model...

26 July 2021 6,253 4 View

What would be the best way to combine several denoised images?

I have generated denoised images using several models and would like to ensemble at the prediction level to achieve superior denoising results. What would be the best way to combine (averaging,...

10 March 2021 2,270 1 View

How to choose the best segmentation model using the area under the precision recall curve, IOU and Dice metrics?

I am using several U-Net variants for a medical image segmentation task. I get the following values for the performance measures including Dice, IOU, Area under receiver-operating characteristic...

27 December 2020 7,525 3 View

How to perform pixel-level mappings between different views of chest x rays?

I have a frontal and lateral chest x ray projection for a given patient as shown in the attached figures. I am thinking about performing pixel-level mappings across these views. What are the steps...

26 October 2020 7,617 3 View

How to learn more about SPSS and its Application?

I would like to learn more about SPSS and Its application especially in regards to data analysis. Please suggest me how I can learn more about it. Thank you so much.

11 August 2024 9,101 4 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,138 1 View

Using OBD technique i am trying to measure laser induced shockwaves velocity i found that at start velocity increases and then decay?

i am unable to interpret why its increases in start as shown in figure

11 August 2024 2,179 1 View

Baseline drift in HPLC? What causes this?

Hello, Why do i see this baseline drift when i compare my blank (black) to the sample (blue)? Any suggestions as to why this happened? Thank you!

11 August 2024 3,770 4 View

Text-Communication from the M1 Hand Area using BCI—and then there is Elon Musk?

Willett, Shenoy et al. (2021) have developed a brain computer interface (BCI) that used neural signal collected from the hand area of the motor cortex (area M1) of a paralyzed patient. The...

10 August 2024 7,180 0 View

Has anyone applied Python in the field of textile engineering for data analysis, automation, or smart textiles?

I'm currently exploring the application of Python in textile engineering, specifically in areas like data analysis, process automation, and the development of smart textiles. I'm interested in...

10 August 2024 7,429 2 View

Which Scopus Journal provides the most affordable fees?

"PUBLISHING IN A SCOPUS JOURNAL" Researchers are now at a cross road. The critical need to publish in a Scopus or ISI, etc journal is ever vital. Journal Publication fees must be submitted....

10 August 2024 8,621 1 View

Geotechnical Engineering (Proceedings of the ICE) time review?

Hello everyone, I recently submitted an article to Geotechnical Engineering (Proceedings of the ICE), and the current status has been listed as "EiC Pre-assessment: Ready" for the past 20 days. I...

10 August 2024 6,493 1 View

Seeking Advice on Viability and Execution of Undergraduate Thesis Topic?

Hello everyone, I am currently developing a thesis proposal and would appreciate your input on its viability and how to effectively carry it out. My proposed topic is: "Does the perceived threat...

10 August 2024 8,992 0 View

How can I use the cif data obtained from rietveld refinement extracted via gsas2, for microstructural analysis using ETEX software?

09 August 2024 7,718 0 View

Athar Mutahari

I think

Energy state of protein and Ligand (to gain structural stability) It should be lowest. can be achieve by changing dimentions of protein and ligand.

Binding affinity between protein and ligand.

Mohammad Tarek

binding FREE energies or docking scores, you may consider descriptors of lipinski rule also for ranking.