I guess that you consider many signalling pathways to be pathways that are not metabolic?

e.g. Clotting cascade

Complement cascade

Phosphorylation relays

G-protein coupled receptor cascades (can involve diverse effects such as protein complexes forming and breaking, calcium influx, localisation)

Also, eukaryotic cells in particular show extremely complicated trafficking pathways that are metabolic in some cases, but are also used for control of cellular behaviour (e.g. controlled release vesicles containing some neuroactive signals at synapses).

Is this what you were thinking?

I guess that you consider many signalling pathways to be pathways that are not metabolic?

e.g. Clotting cascade

Complement cascade

Phosphorylation relays

G-protein coupled receptor cascades (can involve diverse effects such as protein complexes forming and breaking, calcium influx, localisation)

Also, eukaryotic cells in particular show extremely complicated trafficking pathways that are metabolic in some cases, but are also used for control of cellular behaviour (e.g. controlled release vesicles containing some neuroactive signals at synapses).

Is this what you were thinking?

I supposse you can include certain regulatory pathways as non metabolic ones. For example Specific protein 1(Sp1) is a regulatory transcription factor which may act as an enhancer of transcription promotion. There are many pathways that lead Sp1 to enter the nucleus and regulate the transcription of certain genes. Usually a promoter transcription factor is also necessary for Sp1 activity.

Dear Nicholas and Tomas,

Thank you for your answers.

I think signaling pathways are nice examples as non-metabolic pathways.

Even though, they could promote metabolic responses.

Best,

Arman