How do cell knows when to divide and to stop growing.
Cancer cells are characterized by uncontrolled proliferation, fast growing, more activity, and abnormal morphological appearance, while normal cells are not.
Cells grow when the environment and food is at its optimum. As cells grow, their cytoplasm gets bigger. As surface-area-to-volume ratio gets smaller, it gets harder to accept nutrients from outside of the cell, and cell starts stopping the growth. To continue, it does mitosis division (in somatic cells of eukaryotes), and produces two smaller cells with higher surface-area-to-volume ratio, thus, they can again start growing. That is the main principle of cells growth. But control of cells growth is done by cell cycle proteins. When there is a problem in regulation of cell cycle proteins, either of these done:
-cell ceases to continue living
-cell is converted to cancer cell
For more information, you can see the review paper attached.
I wish it is hepful.
Kind Regards.
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