What are the current open problems on bubble dynamics research, especially in the field of biological applications?

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Claus-Dieter Ohl

An interesting area is how multiple bubbles are interacting with a tissue and cause fragmentation/liquification. For example in histotripsy the concerted action of cavitation fragment tissue. How bubbles achieve this is an open question and has relevance for the application in tumour therapy.

Khaled G. Mohamed

Dear Claus-Dieter Ohl,

Is there any published trials to solve this problem?

With Best Regards

Not that I know. You may want to check the proceedings of the recent ISTU meeting for groups working on it.