Early oral cavity cancer is best managed with surgery with/out adjuvant therapy. However several centres do prescribe radiotherapy/Chemoradiotherapy for such lesion.
What is the existing literature on use of RT as definitive therapy?
What is the difference in survival between RT and surgery in early oral cavity cancer?
The French, which are among the most active in brachytherapy (curiethérapie), have a well-outlined set of guidelines for the surgical and non-surgical management of oral cavity squamous cell carcinomas.
It is in French but you should be able to decipher and study the algorithms.
http://oncologik.fr/referentiels/oncolor/carcinome-epidermoide-de-la-cavite-buccale
In pur insititute we prefer surgery to radiotheraph in eary cases of oral cancers.
Thanks Dr Ezzat.
Surgery is the best modality.
We were interested in literature that's support the same.
There are a few studies
1 randomized trial which was terminated due to results favoring surgery
DOI: https://doi.org/10.1016/S0936-6555(98)80055-1
Another large database of NCDB
which compared surgery and radiotherapy as primary modality treatment showed results in favour of surgery
https://doi.org/10.1177/0194599817746909
I appreciate professor Aseem for his excellent answer which summarized the subject.
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