Though many research groups are active in making this device from so many years, why nobody has come up yet with a great accuracy? I know calibration is one of the toughest parts.
Thanks Dr. Kamal. Could you please share me the resource where I can see the device? I had heard about a few, but those are not trustworthy as far as accuracy is concerned.
Short term use of CGMS can be beneficial in patients with diabetes to detect nocturnal
hypoglycemia, the dawn phenomenon, and postprandial hyperglycemia and to assist in the management of hypoglycemic unawareness and when significant changes are made to their diabetes regimen (such as instituting new insulin or to pump therapy)
Source - National Medical Policy, Continuous Glucose Monitoring Devices, Policy Number: NMP333, Health net, Effective Date*: January 2007, Updated: June 2104
The following article discusses the issue:
Accuracy of the Non-Invasive Glucose Monitoring Device Pendra® compared to Alternate Site Glucose Measurements at the Lower Forearm during Dynamic Blood Glucose Changes in Type 1 by Forst et al.
See the full article at the link:
http://professional.diabetes.org/Content/Posters/2004/p434-P.pdf
Abstract::
The use of alternative methods for glucose monitoring in diabetes mellitus
receive increasing attention. The new developed impedance spectroscopy based
Pendra® allows continuous monitoring of glucose variations at the lower forearm
in a completely non invasive approach. However, recent studies with various
invasive methods revealed some discrepancies in blood glucose readings at the
lower forearm compared with the fingertip, especially during rapid glucose
changes.
In our investigation, glucose readings obtained from the lower forearm using
Pendra® and an alternate site technique (AST) were compared with blood glucose
measurements obtained from the fingertip during a standardized glucose
challenge experiment in 12 type 1 diabetic patients (5 female, 7 male, age:
31.5±8.7 years). Patients ingested 75 g of liquid glucose and after 2 hours, insulin
was applied intravenously or subcutaneously in a randomized sequence to
achieve a rapid or modest blood glucose decline. Blood glucose was measured
every 15 min and compared with reference glucose measurements (glucose
oxidase; Super GL) obtained from the fingertip.
During increasing blood glucose values, no significant differences in blood
glucose measurements could be observed between the different methods or skin
locations. During both, rapid and modest blood glucose declines a significant time
shift in glucose measurements could be observed with the AST (p
Thanks a lot Prof. Rababah for sharing this resource. It's a good article.
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