I think most known volunteers for the trial vaccines have died! Daily declared discovered cases were logged samples in the molicular labs that were just being tested, [slow process and few tests] - it doesn't relate to the daily rate or true description of COVID-19 statistical variables among the Nations' Population.[lost vital information]. People are lost in technical terms and conflicting expert opinions, example is asymptomatic or asymptotic solution curves!
Most treatments and vaccines were reportedly just in the pre-clinical stages to about three(3) in phase 2, and one in phase 3. All have side effects! The curve could be down but definitely will be asymptotic!
Now, why the few tests, and delays in the trials of the vaccines, such as the #Morderna? What are the challenges to finding an effective and consistent solutions to the Novel Coronavirus , SARS-CoV-2, (political, social, public health care, treatments, therapy and the preventive measures also vaccines)?
Can we assess the situation for people/patients with history of recent immunosuppressive therapy, children, pregnant women and the elderly? We know that "COVID-19 is most likely to be lethal to older adults with pre-existing health conditions [and those with immune system problems]", Przemysław Tomasik, Filipina Krótki, Mateusz Jońca, Tomasz Anyszek (2020).
Let's continue to maintaining good health through health promotion activities, following the 'keeping safe rules' and preventative lifestyle. I think most known volunteers for the vaccines have died! Discovered cases were logged samples in the labs that were just being tested, it doesn't relate to the daily rate or true statistics among the population.[conserved vital information]
Most treatments and vacine were just in pre-clinical stages to just about three(3) in phase 2, and one in phase 3. All have side effects! Why the few tests, and delays in the trials of the vaccines, like #Morderna. What are then the challenges to finding an effective and consistent on to the Novel Coronavirus (SARS-CoV-2)?
mune system problems]", Przemysław Tomasik, Filipina Krótki, Mateusz Jońca, Tomasz Anyszek (2020), "COVID-19 rapid antibody tests ". Let's continue to maintaining good health through health promotion activities, following the 'keeping safe rules' and preventative lifestyle.
There have been reports of the state, safety and cost of our laboratories. Also the availability, maintenance and efficiency of the equipments and testing approach, especially in developing countries even though they have experienced researchers, care givers, pathologist sand laboratory experts! Some government, particularly in developing countries have resulted to lies, and inflated data to benefit from international aids and funds. Pathetic!
A major problem is the cost and use of the molicular & cellular approach and equipment to finding the virus and studying it's effects, nature or structure and possible inhibitors to it's protein eating spikes. Adequate data are not available, enough surveillance and testing are not done! Daily discovered cases were logged samples just being tested. Death rate and odds of recovering are the only reliable Statistics.
Conflicting remarks by WHO Officials and Researchers, a controversial one was a Maria Van Kerkhove, the WHO’s technical lead on the Covid-19 pandemic who caused controversy with her statement that it was rare for assymptotic transmission, made it very clear that the actual rates of asymptomatic transmission aren’t yet known. She acknowledged later that her use of the phrase “very rare” had been a miscommunication.
Most treatment and vaccines are still within pre-clinical to phase 1. Today, however, a significant breakthrough in the area of Vaccine is the Moderna’s vaccine, mRNA-1273, is a synthetic messenger RNA that encodes for a protein found on the surface of the novel coronavirus. By compelling cells to produce that protein, the vaccine would spur an immune response, causing the body to generate antibodies that would protect against infection. Further human trials have been delayed, possibly will continue this July. See: STAT's Covid-19 Drugs and Vaccines Tracker
Fourteen Covid-19 vaccines are currently in human trials, according to the Milken Institute, including entrants from Inovio, CanSino, AstraZeneca, and Moderna. More are expected to start soon, including entrants from Merck, Johnson & Johnson, and Sanofi. In total, 178 vaccines are in various stages of development.
We must all contribute, in our obliged and responsible state considering our disposition, expertise, position and society. Our options include social responsibility as a function of the right Social Policies, education and support; Political supports indicated by political will, control and effectiveness; and exploring particular relevant scientific and technological communities for coordinated, synergized and most likelihood solution to the pandemic, and assymptotic carry-over or contingency effects.
Maintaining trust of our experts, and government policies is important. We love our freedom, there is panic on how business and we would survive. Effects of being an atheist, demonstrating against government policies, and deviant behaviors are obvious in USA, Italy and Europe as a whole. We've learned, we must always be prepared for future threats. :)
The only solution is to stay away from the virus. There will never be a vaccination since coronavirus has always been resistant to its production
Seriously? Andrew Paul McKenzie Pegman .. . Thanks for your response. Pls, stay safe.
Yes, I'm a veterinarian and there has never been a coronavirus vaccine for pets or for the human cold for that matter
Abiodun Christian Ibiloye
Perhaps, we are going to get a promising repurposed antiviral drug, Favipiravir as a first line therapy. 96% patients tested RT-PCR negative by the 10th day of the clinical trial who received Favipiravir. In Bangladesh, a Double-Blind Placebo Control Clinical Trial on 50 patients disclosed the prospective outcome of the study today ( July 7, 2020). Despite the study covered a small sample size, its result is so promising. It is going to enlarge its size to the next phase trial. You may find the elaboration from the following link.
https://tbsnews.net/coronavirus-chronicle/japanese-covid-19-drug-expedites-recovery-during-clinical-study-103204
Thank you so much Md. Jamal Hossain for the information and the link. Another promising vaccine is the Morderna, [experimental Covid-19 vaccine being developed by the drug giant Pfizer and the biotech firm BioNTech spurred immune responses in healthy patients, but also caused fever and other side effects, especially at higher doses.]
Moderna’s vaccine, mRNA-1273, is a synthetic messenger RNA that encodes for a protein found on the surface of the novel coronavirus. By compelling cells to produce that protein, the vaccine would spur an immune response, causing the body to generate antibodies that would protect against infection.
Fourteen Covid-19 vaccines are currently in human trials, according to the Milken Institute, including entrants from Inovio, CanSino, AstraZeneca, and Moderna.
See for further information:
1. Vaccines: https://www.statnews.com/feature/coronavirus/drugs-vaccines-tracker/#vaccines
2. Treatment: https://www.statnews.com/feature/coronavirus/drugs-vaccines-tracker/#treatments
*We really hope for breakthroughs and significant changes this July and August.
Abiodun Christian Ibiloye
I am so glad for your response. I was talking about a curative treatment option of the drugs which are intended to be repurposed. We must find a vaccine to prevent this novel treat and scientists are trying day and night to develop an approaved vaccine. Amongst more than hundred vaccines, very few are going on Phase III trial. Hopefully, moderna will touch the ultimate goal very soon. Oxford vaccine or Sinovac are also promising. We want to be free from this pandemic. Thank you so much for your shared link regarding the most talked fighting tools against the SARS-CoV-2 infection.
Two important challenges - pin pointed vaccine and social distancing during the unlock phase
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