What are the best receptors for the determination of in silico anti-inflammatory property of a ligand?

Nantenaina Tombozara @Nantenaina-Tombozara

14 July 2022 1 9K Report

We are looking for receptors in order to perform in silico studies of some antalgic and anti-inflammatory ligands isolated from plants and have been tested in vivo.

A part from COX 2, IL-6, TNF-alfa, could anyone propose other important receptors?

Prasad Dhiwar

You can go for NF-KB, IgA IL-1, Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors.

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