Applications of bioinformatics in medicine is a key factor in technological advancement in the field of modern medical technologies.
In which areas of medical technology are the technological achievements of bioinformatics used?
What are the applications of bioinformatics in medicine?
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in genomics, proteomics...Scientists in the throes of research use an extensive data bank to access structural information on proteins and nucleic acids. Meanwhile, geneticists use a highly specialized form of software to analyze the hybridization pattern of DNA chips. The past decade has been tremendously successful for biotechnology and pharmaceutical industries. This success has been a result of astounding technical advancements in genome sequencing (genomics), protein identification (proteomics), and data analysis-collectively called bioinformatics ... Rashidi, H. H., & Buehler, L. K. (1999). Bioinformatics basics: applications in biological science and medicine. CRC press.
From pediatrics side, Genomictechnologies produces a huge amount of information, unprecedented in biology. Bioinformatics can help to addresse these needs in data acquisition, storage, processing and integration that research in genomics generates.
Through combining computer science, mathematics, physics, and biology, Bioinformatics helps us to analyze genome sequence data including human genome data to identify mishaps associated with diseases. It is useful in genomics to characterize and quantify genes, and also in Proteomics, Transcriptomics, Drug Discovery as well as Personalized Medicine.
It will be useful for precisely work on Medicine using biological data
in genomics, proteomics...Scientists in the throes of research use an extensive data bank to access structural information on proteins and nucleic acids. Meanwhile, geneticists use a highly specialized form of software to analyze the hybridization pattern of DNA chips. The past decade has been tremendously successful for biotechnology and pharmaceutical industries. This success has been a result of astounding technical advancements in genome sequencing (genomics), protein identification (proteomics), and data analysis-collectively called bioinformatics ... Rashidi, H. H., & Buehler, L. K. (1999). Bioinformatics basics: applications in biological science and medicine. CRC press.
In molecular medicine... Altman, R. B. (1998). Bioinformatics in support of molecular medicine. In Proceedings of the AMIA Symposium (p. 53). American Medical Informatics Association.
In precision med... Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small group or even individual patients based on their genetics, environment and lifestyle. Precision medicine relies heavily on developments in systems biology and omics disciplines, including metabolomics. Combination of metabolomics with sophisticated bioinformatics analysis and mathematical modeling has an extreme power to provide a metabolic snapshot of the patient over the course of disease and treatment or classifying patients into subpopulations and subgroups requiring individual medical treatment.... Azad, R. K., & Shulaev, V. (2019). Metabolomics technology and bioinformatics for precision medicine. Briefings in bioinformatics, 20(6), 1957-1971.
Bioinformatics will serve to identify susceptibility genes and illuminate the pathogenic pathways involved in illness, and will therefore provide an opportunity for development of targeted therapy. Recently, potential targets in cancers were identified from gene expression profiles. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1122955/
As an interdisciplinary field of science, bioinformatics combines biology, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for in silico analyses of biological queries using mathematical and statistical techniques. https://en.m.wikipedia.org/wiki/Bioinformatics
The application of bioinformatics is proving quite useful in this field as the human genome has helped unlock the genetic components for many diseases. Potential applications include drug discovery, personalized medicine, preventative medicine and gene therapy. https://www.usfhealthonline.com/resources/key-concepts/what-is-bioinformatics/
Bioinformatics applied to the whole genome sequences and their mutations could predict de development of certain type of cancer at a given age. The cybernetic of physiological parameters could also predict the evolution of a given disease. Bioinformatics is also able to test in silico the interaction(s) of given molecules on their targets.
Bioinformatics, as a subdiscipline of biology and computer science, is concerned with the acquisition, storage, analysis, and dissemination of biological data, most often DNA and amino acid sequences.
https://www.genome.gov/genetics-glossary/Bioinformatics
Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim of better understanding the genetic basis of disease, unique adaptations, desirable properties...
https://en.m.wikipedia.org/wiki/Bioinformatics
There is a tremendous application of bioinformatics in the field of homology and similarity tools, protein function analysis, personalised medicine, Gene therapy, Drug development, Comparative Studies and also climate change studies. https://www.longdom.org/scholarly/applications-of-bioinformatics-journals-articles-ppts-list-2874.html
machine learning-based bioinformatics has been very useful in precision medicine. It can be used for signature-building (based on omics data or a combination of omics and clinical features) to stratify patients for prognosis, drug treatment, early disease detection etc. and biomarker discovery. In order to make machine learning accessible for medical researchers, we have developed a no-code auto-machine learning platform. Our beta version is free, just sign up https://demo.solvergen.com/accounts/login/
Kindly check https://www.longdom.org/scholarly/applications-of-bioinformatics-journals-articles-ppts-list-2874.html
Also check https://www.genome.gov/genetics-glossary/Bioinformatics
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