What are the acute and long term effects of chemoradiation in paediatric cancer patients' haematological and immunological parameters?

More Manisha Roy's questions See All

Do NK cells possess DNA?

Nucleic acids

04 May 2018 2,787 0 View

Do NK cells possess DNA?

Nucleic acids

04 May 2018 7,994 0 View

What buffer to use fresh frozen biopsy specimens?

So that it can be stored in below 80 degree conditions.

01 February 2018 517 3 View

What are the methods to count Natural Killer cells in human peripheral blood

Also, I have come across NK cell whole blood count & percentage wise count. Which is a better option if I need to use it as tumour biomarker?

04 May 2017 9,279 3 View

What is the annual incidence rate of high grade glioma in India and globally?

With refrences

04 May 2017 9,525 0 View

Which universal primer I should use for pET6xHN-N?

Both forward and reverse?

06 July 2016 6,585 3 View

Can I use DH10B in place of Top 10 E.coli competent cells?

For cloning purpose.

04 May 2016 8,447 0 View

What does pET stands for, in pET32a?

Protein expression vector

04 May 2016 2,736 1 View

Which of the Covid-19 Vaccines would elicit the best immunoprotection and why?

I want to know which of the available Covid-19 Vaccines would elicit the best immunological response and why

02 March 2021 1,388 3 View

Can we distinguish the type of free fluid inside the pelvic and abdominal cavities whether blood or serous fluid using the ultrasound?

during ultrasound examination of acute abdomen, sometimes we see free fluid , can we know the type of fluid ,whether blood or not , using ultrasound only? if yes , what are the sonographic...

01 March 2021 7,476 4 View

Experimental Design: How deal with pseudreplicates with immunological and clinical-chemical paramaeters?

Hello everybody, I am investigating the influence of a toxinon various clinical-chemical and haematological parameters in fish. I have three treatments (control, low dose, high dose) in my...

24 February 2021 1,243 1 View

Looking for advices and tips to improve the staining and the gating strategy in human blood?

Hi, I am staining a human blood with CD19, CD3,CD14 and CD16. My gating strategy in FlowJo goes like this: - First, I gate a general population SSC-A VS FSC-A => Then gate for single cells, =>...

21 February 2021 5,724 4 View

Which Journals would you advise to submit a Letter which briefly talks about neurosurgical treatment of neuro-oncological patient during Sars-COV-2?

Possibily not an open access journal which does not add any publishing costs once being accepted. Thank you in advance

09 February 2021 717 6 View

ACE2 Blotted as a double band?

Hello, I have recently run a western of Vero cells for ACE2. I detected ACE2 at the correct size, but it presents as a double band. The sample was prepared by lysing cells in 1X Laemmli...

07 February 2021 6,973 3 View

Can you polarize Jurkat cells into different T helper subsets?

I am wondering if anyone has had success with in vitro polarization (via cytokines) of Jurkat cells. My goal is to understand the affect of a drug on Treg induction and differentiation. I...

12 January 2021 3,606 2 View

It does not appear logistically possible to vaccinate everyone for COVID. So what's the point?

Public health authorities claim that no one is safe from COVID-19 until every one is safe. This has translated into a goal to vaccinate everyone who can be vaccinated. Logistically, however, it...

06 January 2021 4,269 12 View

How the problem of water scarcity in hilly region can be solved ?

the area received high rainfall, only last 3 months of hydrological year faces acute water shortage even for drinking the solution for this may be rainwater harvesting now how value...

25 December 2020 2,408 4 View

Will the serum of healed patients can be considered to make a vaccine/drug against COVID-19?

22 December 2020 2,180 4 View

Brian Hanley

The effects depend on dose of chemo, dose of radiation, specific chemo drug(s), type of radiation treatment. For instance, treatment with gamma radiation following chemo and surgery for a myosarcoma will have different effects and dose than for glioma. (With glioma, since survival rates are so low it hardly matters.) Contrast that in turn with radiation for osteosarcoma which would often be delivered by strontium-89. Etc. If you want to understand it better, you can read this book.

https://www.amazon.com/Radiation-Exposure-treatment-modern-handbook-ebook/dp/B00D7KLQYY

It does not appear that you have a practical need or I would make recommendations for optimizing treatment.