What are some of the most frequently used quantitative methods in HTA. Which one of the Multi Criteria Decision Making method are used in HTA? What are advantage and disadvantages?
To answer that fairly, It requires me to write a textbook, so I apologize for my brief answer.
Which one of the Multi Criteria Decision Making method are used in HTA?
This varies widely depending on healthcare organizations/countries. Each country has its own criteria/framework and even in UK NICE/NHS where I qualified is evolving constantly sometimes inconsistent (ICER threshold in general vs orphan disease vs cancer fund, value of year of life in NHS vs HT Treasury) . Some countries do not use MCDM or HTA !
What are some of the most frequently used quantitative methods in HTA?Economic evaluation most frequently Incremental Cost Effectiveness Ratios (ICER). Can be from narrow provider perspective or wider societal perspective. Most common models I have seen in NHS/NICE appraisals are decision tress, Markov, Partitioned survival models and to less degree microsimulation. Rare use of discrete event simulation because you get same results with Markov for less computational labor.
In that case, I would think that you are looking for the best method or for appropriate methods for the specific assessments you want to do. Those may be different depending on the different interventions you are assessing and on the data that available to you concerning those interventions.